Zogulitsa

Immunoassay pakutsimikiza kwa in vitro kuchuluka kwa IL-6 (Interluekin-6) m'magazi athunthu amunthu, seramu ndi plasma.

IL-6 ndi polypeptide ya interleukin, yopangidwa ndi maunyolo awiri a glycoprotein;Imodzi inali tcheni cha α chokhala ndi molekyulu yolemera 80kd.Wina ndi unyolo wa β wokhala ndi kulemera kwa molekyulu ya 130kd, yomwe imapangidwa mwachangu panthawi yotupa kwambiri monga matenda, kuvulala mkati ndi kunja, opaleshoni, kuyankha kupsinjika, kufa kwaubongo, tumorgenesis ndi zina.IL-6 imakhudzidwa ndi kuchitika ndi chitukuko cha matenda ambiri.Mulingo wake wa seramu umagwirizana kwambiri ndi kutupa [1-2], matenda a virus [3] ndi matenda a autoimmune.Kusintha kwake kuli koyambirira komanso kotalika kuposa mapuloteni a C-reactive (CRP) ndi procalcitonin (PCT) . Kafukufuku wasonyeza kuti IL-6 imakula mofulumira pambuyo pa matenda a bakiteriya, imawonjezeka pambuyo pa 2h, pamene mapuloteni a C-reactive amawonjezeka mofulumira pambuyo pa 6h [4] .Milingo ya IL-6 yowonjezereka mu matenda osiyanasiyana otupa ndi osiyana.IL-6 ingagwiritsidwenso ntchito kuyesa kuopsa kwa matenda ndi momwe zimakhalira.Kuwona kwamphamvu kwa interleukin - 6 mlingo kumathandizanso kumvetsetsa momwe matenda opatsirana akuyendera komanso momwe angayankhire chithandizo.