Zogulitsa

Immunoassay pakutsimikiza kwa in vitro kuchuluka kwa ndende ya D-Dimer mu seramu yamunthu ndi plasma.Osapatula pulmonary embolism mkati mwa mphindi 15 mukakhala pafupi ndi odwala.

D-dimer ndi polima wa fibrin wa zidutswa za DD za mamolekyu olumikizana ndi ma fibrin opangidwa pansi pa enzymolysis ya plasmin.Kusinthasintha kwamphamvu pakati pa plasmin ndi inhibitory enzyme kumasungidwa mwa anthu athanzi kuti kufalikira kwa magazi kuchitike moyenera.Dongosolo la fibrinolytic m'thupi la munthu limagwira ntchito yofunika kwambiri pakusunga kukhazikika kwa khoma lamtsempha wamagazi ndikuyenda kwa magazi komanso kukonza minofu.Kusunga yachibadwa zokhudza thupi boma, pa nkhani ya zoopsa kapena mtima kuwonongeka , thrombus mapangidwe angalepheretse kutaya magazi kuonongeka mitsempha.Pansi pa pathological mikhalidwe, pamene coagulation imapezeka m'thupi, thrombin imagwira ntchito pa fibrin, ndipo dongosolo la fibrinolytic limatsegulidwa kuti liwononge fibrin ndikupanga zidutswa zosiyanasiyana.R chain imatha kulumikiza zidutswa ziwiri zomwe zili ndi D fragment kupanga D-dimer.Kuwonjezeka kwa mlingo wa D-dimer kumayimira mapangidwe a magazi mu mitsempha ya mitsempha.Ndi chizindikiro chodziwika bwino cha pachimake thrombosis, koma sichidziwika.