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Ngakhale COVID yanthawi yayitali imakhala ndi zinsinsi zambiri, ofufuza apeza zowunikira pamtima mwa odwalawa, ndikuwonetsa kuti kutupa kosalekeza ndi mkhalapakati.
Pagulu la odwala 346 omwe anali athanzi kale a COVID-19, ambiri mwa iwo omwe adakhalabe ndizizindikiro pambuyo pa miyezi inayi, kukwera kwa zizindikiro za matenda amtima komanso kuvulala kwamtima kapena kusagwira bwino ntchito kunali kosowa.
Koma pali zizindikiro zambiri za mavuto a mtima wa subclinical, lipoti Valentina O. Puntmann, MD, University Hospital Frankfurt, Germany, ndi anzake ku Nature Medicine.
Poyerekeza ndi zowongolera zopanda kachilomboka, odwala a COVID anali ndi kuthamanga kwa magazi kwa diastolic kwambiri, kuchuluka kwa zipsera zopanda ischemic za myocardial chifukwa chakulitsidwa mochedwa kwa gadolinium, kuwoneka kosagwirizana ndi hemodynamically pericardial effusion, komanso pericardial effusion.<0,001). <0.001).
Kuphatikiza apo, 73% ya odwala a COVID-19 omwe ali ndi zizindikiro zamtima anali ndi mapu a MRI (CMR) apamwamba kwambiri kuposa anthu asymptomatic, kuwonetsa kutupa kwa myocardial komanso kudzikundikira kwakukulu kwa pericardial kusiyana.
"Zomwe tikuwona ndizabwino," Puntmann adauza MedPage Today."Awa ndi odwala omwe kale anali odwala."
Mosiyana ndi zomwe nthawi zambiri zimaganiziridwa kuti ndi vuto la mtima ndi COVID-19, zotsatirazi zimapereka chidziwitso kuti odwala omwe ali ndi vuto la mtima lomwe linalipo kale amatha kugonekedwa m'chipatala akudwala kwambiri komanso zotsatira zake.
Gulu la Puntman lidaphunzira anthu opanda vuto la mtima kuyesa kumvetsetsa momwe COVID-19 imakhudzira, pogwiritsa ntchito zithunzi za MRI za odwala omwe amapita kuzipatala zawo kudzera mwa madotolo apabanja, malo oyang'anira zaumoyo, zida zotsatsira zomwe zimafalitsidwa ndi odwala pa intaneti.Magulu ndi mawebusayiti..
Puntmann adanenanso kuti ngakhale ili ndi gulu losankhidwa la odwala omwe nthawi zambiri sangaimirire odwala a COVID-19, sizachilendo kuti odwalawa apeze mayankho kuzizindikiro zawo.
Zofufuza za Federal zikuwonetsa kuti 19 peresenti ya akuluakulu aku America omwe ali ndi COVID anali ndi zizindikiro kwa miyezi itatu kapena kupitilira apo atadwala.Pakafukufuku wapano, kutsata kuwunika kwapakati pa miyezi 11 pambuyo poti matenda a COVID-19 adawonetsa kusakhazikika kwamtima mwa 57% ya omwe adatenga nawo gawo.Omwe adakhalabe ndi zizindikiro anali ndi edema ya myocardial yofalikira kuposa omwe adachira kapena alibe zizindikiro (zachilengedwe T2 37.9 vs 37.4 ndi 37.5 ms, P = 0.04).
"Kutenga nawo gawo pamtima ndi gawo lofunikira pakuwonetsetsa kwanthawi yayitali kwa COVID - chifukwa chake dyspnea, kusalolera, tachycardia," adatero Pontman poyankhulana.
Gulu lake linanena kuti zizindikiro zamtima zomwe adaziwona zinali "zogwirizana ndi chotupa chotupa chapamtima, chomwe chingafotokoze, mwina mwa zina, maziko a pathophysiological azizindikiro zamtima zosalekeza.Makamaka, kuvulala koopsa kwa myocardial kapena matenda a mtima sizomwe zidalipo kale ndipo zizindikiro sizikugwirizana ndi tanthauzo lachikale la viral myocarditis. "
Katswiri wa zamtima komanso wodwala wa nthawi yayitali wa COVID Alice A. Perlowski, MD, adawonetsa zofunikira zachipatala polemba pa tweet kuti: "Kafukufukuyu akuwonetsa momwe zozindikiritsira zachikhalidwe (pankhaniyi CRP, minofu calcin, NT-proBNP) sizinganene nkhani yonse. ”., #LongCovid, ndikuyembekeza kuti asing'anga onse omwe amawona odwalawa akugwira ntchito athana ndi mfundo yovutayi."
Mwa akulu 346 omwe ali ndi COVID-19 (azaka 43.3, akazi 52%) adawonetsedwa pamalo amodzi pakati pa Epulo 2020 ndi Okutobala 2021, pakatikati pa masiku 109 atadziwika, chizindikiro chodziwika bwino chamtima chinali kupuma movutikira (62% ), palpitations (28%), kupweteka pachifuwa kwachilendo (27%), ndi syncope (3%).
"Kudziwa zomwe zikuchitika pakuyezetsa mtima kwanthawi zonse ndizovuta chifukwa ndizovuta kuzindikira zovuta," adatero Puntmann.“Zina mwa izo zimakhudzana ndi matenda omwe amayambitsa…Chifukwa chake, sitinawawone ali m'gawo lochepetsedwa. ”
Gululi likukonzekera kupitiliza kutsatira odwalawa kwa nthawi yayitali kuti amvetsetse zomwe zitha kukhala zotsatira zachipatala, poopa kuti "zitha kubweretsa vuto lalikulu la kulephera kwa mtima kwazaka zambiri," malinga ndi tsamba la malowa.Gululi linayambitsanso phunziro la MYOFLAME-19 loyendetsedwa ndi placebo kuti liyese mankhwala oletsa kutupa ndi mankhwala omwe amagwira ntchito pa renin-angiotensin system mwa anthuwa.
Kafukufuku wawo adangophatikiza odwala omwe analibe matenda amtima omwe amadziwika kale, ma comorbidities, kapena kuyezetsa magazi m'mapapo poyambira komanso omwe anali asanagonepo m'chipatala chifukwa cha COVID-19.
Odwala ena 95 pachipatalachi omwe analibe COVID-19 isanachitike ndipo analibe matenda amtima odziwika kapena comorbidities adagwiritsidwa ntchito ngati zowongolera.Ngakhale ofufuzawo adavomereza kuti pakhoza kukhala kusiyana kosadziwika poyerekeza ndi odwala a COVID, adawonanso kugawa kofananako kwa ziwopsezo ndi zaka, jenda, komanso matenda amtima.
Mwa odwala omwe ali ndi zizindikiro za COVID, ambiri anali ofatsa kapena ochepa (38% ndi 33%, motsatana), ndipo asanu ndi anayi okha (3%) anali ndi zizindikiro zazikulu zomwe zimalepheretsa zochitika za tsiku ndi tsiku.
Zomwe zimalosera mosasamala za zizindikiro zamtima kuyambira pakuwunika koyambira mpaka kuyambiranso pakadutsa miyezi inayi (masiku apakati 329 atapezeka kuti ali ndi matenda) anali jenda lachikazi ndipo amafalitsa kukhudzidwa kwa myocardial poyambira.
"Zachidziwikire, chifukwa kafukufuku wathu adangoyang'ana anthu omwe ali ndi matenda a pre-COVID, sananene za kufalikira kwa zizindikiro zamtima za post-COVID," gulu la Puntman linalemba."Komabe, imapereka chidziwitso chofunikira chokhudza mawonekedwe awo komanso chisinthiko chotsatira."
Puntmann ndi wolemba nawo adawulula zolipirira zoyankhula kuchokera ku Bayer ndi Nokia, komanso ndalama zophunzirira kuchokera ku Bayer ndi NeoSoft.
Mawu oyambira: Puntmann VO et al "Matenda ammtima anthawi yayitali mwa anthu omwe ali ndi matenda a COVID-19", Nature Med 2022;DOI: 10.1038/s41591-022-02000-0.
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